Trental

Trental (Pentoxifylline)

A prescription medication designed to improve blood flow and oxygen delivery in conditions caused by poor circulation, such as peripheral artery disease (PAD).

How Trental Works

Trental contains Pentoxifylline, a xanthine derivative that works by:

• Improving Blood Flow: Reduces the thickness (viscosity) of blood, allowing it to flow more easily through narrowed or blocked arteries.
• Enhancing Oxygen Delivery: Increases oxygen supply to tissues, particularly in areas with impaired circulation.
• Reducing Muscle Pain: Relieves pain, cramps, and muscle discomfort associated with intermittent claudication caused by poor circulation.

By improving microcirculation, Trental helps alleviate symptoms and enhances mobility in individuals with peripheral vascular diseases.

Uses of Trental

Trental is prescribed to treat:

• Intermittent Claudication: Pain, cramping, or fatigue in the legs due to reduced blood flow, often associated with peripheral artery disease (PAD).
• Peripheral Vascular Diseases: Conditions affecting blood flow to the limbs, improving overall vascular health.
• Other Circulatory Issues: May be used off-label for other conditions involving impaired blood flow, as determined by a healthcare provider.

Key Benefits

• Improves Circulation: Enhances blood flow to tissues, reducing pain and discomfort caused by poor circulation.
• Supports Mobility: Helps individuals with intermittent claudication walk longer distances without pain.
• Effective Oxygen Delivery: Ensures better oxygenation of tissues in affected areas.
• Well-Tolerated: Generally effective with minimal side effects when used as directed.

Dosage and Administration

Recommended Dosage:

• Typically, 400 mg taken 2-3 times daily, as prescribed by a healthcare provider.
• The dose may be adjusted based on individual response and tolerability.

How to Take:

• Swallow the tablet whole with a glass of water; do not crush or chew the tablet.
• Take the medication after meals to reduce stomach discomfort.
• Consistency is important; take Trental at the same time(s) every day as directed by your doctor.

Precautions and Warnings

Not Suitable For:

• Individuals allergic to Pentoxifylline, xanthine derivatives (e.g., caffeine, theophylline), or any inactive ingredients in Trental.
• Patients with severe bleeding disorders or recent hemorrhages.
• People with a history of recent stroke or heart attack.

Use With Caution:

• If you have kidney or liver impairment, as dosage adjustments may be necessary.
• In individuals taking anticoagulants (blood thinners), as Trental may increase bleeding risk.
• Avoid alcohol consumption, as it may increase the risk of side effects.

Side Effects

Common Side Effects:

• Nausea
• Dizziness
• Headache
• Stomach discomfort or bloating

Less Common Side Effects:

• Flushing
• Skin rash
• Weakness

Rare but Serious Side Effects:

• Severe allergic reactions, such as swelling, itching, or difficulty breathing
• Bleeding or unusual bruising
• Chest pain or irregular heartbeat

If you experience severe or persistent side effects, discontinue use and consult a healthcare provider immediately.

Storage Instructions

Store Trental at room temperature (15-30°C or 59-86°F) in its original packaging. Keep it away from moisture and direct sunlight. Ensure it is out of reach of children and pets.